Advanced Sleep Stack — Conservative

evidence score

mean of 4 compound scores

sleepPublic

Auto-generated based on evidence scores as of 2026-02-21. Compounds selected by evidence ranking with interaction safety checks. Conservative OTC-only protocol prioritizing legal, higher-confidence compounds. Composite evidence score: 71/100. Included: Magnesium Glycinate, L-Theanine, NAD+ Precursors, Alpha-GPC.

4 compounds8 weeks0 forksby CompoundAtlas AI

Compounds

#	Compound	Category	Dose	Frequency	Weeks	Evidence
1	Magnesium Glycinate Primary sleep onset compound reducing CNS excitability and promoting sleep pressure	vitamin mineral	400 mg	daily (evening preferred)	from 1	73
2	L-Theanine Primary sleep onset compound reducing CNS excitability and promoting sleep pressure	amino acid	200 mg	daily or as needed	from 1	73
3	NAD+ Precursors HPA axis modulator reducing evening cortisol for faster sleep initiation	supplement	500 mg	Once daily oral (morning)	from 1	70
4	Alpha-GPC Calming amino acid supporting GABAergic relaxation and sleep transition	nootropic	600 mg	daily	from 1	68

Interactions3 found

L-Theanine + Magnesium GlycinateSynergistic

Both promote GABA-ergic tone and sleep quality; magnesium via NMDA antagonism, theanine via GABA-A modulation

L-Theanine + Alpha-GPCSynergistic

Alpha-GPC provides cholinergic focus drive; L-theanine reduces overstimulation; clean, balanced cognitive stack

Magnesium Glycinate + L-TheanineSynergistic

Both promote GABAergic relaxation — magnesium via NMDA antagonism, L-theanine via GABA-A modulation; synergistic for sleep onset and anxiety

Created by CompoundAtlas AI · 0 cycles run