Trenbolone Acetate

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evidence score

anabolic

Scheduled Substance

tren acetren AFinajet+2 more

Trenbolone Acetate is a veterinary-grade 19-nortestosterone derivative approved for cattle muscle growth (Finaplix-H implants). It is considered the most powerful anabolic steroid used by bodybuilders. With an anabolic:androgenic ratio of ~500:500 vs testosterone's 100:100, it produces dramatic lean mass and strength gains with potent fat loss simultaneously — the only compound that achieves true recomposition at high doses. It does not aromatize to estrogen but binds progesterone receptors. Its side effect profile is among the harshest of any AAS: cardiovascular, neurological, androgenic, and mental health effects. NOT for beginners. Scheduled III controlled substance in the US; no human medical use.

Evidence

No score yet

Safety

Unknown safety profile

Clinical Status

No formal phase listed

Research Sync

Not synced yet

Dosing

Typical

300 mg

150 mgRange600 mg

Frequencyevery other day (EOD) due to short half-life

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Pharmacology

Half-life~3 days (acetate ester)

OnsetStrength and vascularity improvements 1-2 weeks; muscle growth 4-6 weeks

DurationRapid clearance with acetate ester; detectable on drug test for months

Routes

intramuscular_injection

Evidence Score

—

0 studies indexed

Scoring Factors

Volume(40%)—

Quality(30%)—

Sample Size(10%)—

Consistency(10%)—

Replication(5%)—

Recency(5%)—

Evidence Levels

AScore ≥75 with at least 1 meta-analysis and 3+ RCTs

BScore ≥50 with at least 1 RCT or meta-analysis

CScore ≥25 — observational or animal evidence only

DScore <25 — very limited or preclinical data

Plain-English Snapshot

Trenbolone Acetate is currently categorized as a anabolic compound.

Evidence scoring has not been fully computed yet, so interpret this profile as preliminary.

Safety scoring is incomplete. Start conservatively and monitor carefully.

Core mechanism

Highly potent AR agonist (5x testosterone affinity); direct IGF-1 upregulation; glucocorticoid receptor competition; does not aromatize; progestogenic activity

Practical Context

Strongest current signals

No indexed study summaries yet.

Elevated caution signals

3 severe/high side effect flags