Bromantane
Bromantane is a Soviet-era actoprotector drug developed in the late 1980s for military use under extreme heat and physical stress conditions. Unlike classical stimulants, it works by upregulating the dopamine synthesis enzyme (aromatic amino acid decarboxylase) rather than releasing or blocking reuptake of dopamine. This mechanism makes it non-addictive and less prone to tolerance. It also has unique immunostimulant properties. WADA banned it in 1996 after several positive tests. Russian clinical trials show it reduces fatigue, improves physical performance in heat, and reduces anxiety without sedation. It has a dedicated following in advanced nootropic communities for its clean energy profile.
Evidence
No score yet
Safety
Unknown safety profile
Clinical Status
No formal phase listed
Research Sync
Not synced yet
Dosing
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Pharmacology
Evidence Score
Plain-English Snapshot
Bromantane is currently categorized as a nootropic compound.
Evidence scoring has not been fully computed yet, so interpret this profile as preliminary.
Safety scoring is incomplete. Start conservatively and monitor carefully.
Core mechanism
Upregulates AADC (dopa decarboxylase) gene expression; increases dopamine and serotonin synthesis capacity; non-releasing, non-reuptake mechanism; heat shock protein induction
Practical Context
Strongest current signals
No indexed study summaries yet.
Elevated caution signals
1 severe/high side effect flag